021-51111890
购物车（）
sales@molnova.cn
BAY 2416964
CAS No. 2242464-44-2
BAY 2416964 ( —— )
产品货号. M22445 CAS No. 2242464-44-2
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1369 | 有现货 |
|
| 25MG | ￥2795 | 有现货 |
|
| 50MG | ￥4026 | 有现货 |
|
| 100MG | ￥5289 | 有现货 |
|
| 200MG | ￥7525 | 有现货 |
|
| 500MG | ￥11259 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称BAY 2416964
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
-
产品描述BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Aryl hydrocarbon receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number2242464-44-2
-
分子量387.82
-
分子式C18H18ClN5O3
-
纯度>98% (HPLC)
-
溶解度DMSO:250 mg/mL (644.63 mM; Need ultrasonic)
-
SMILESC[C@@H](CO)NC(=O)c1cc(nn(-c2cnn(C)c2)c1=O)-c1ccc(Cl)cc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1.
产品手册
关联产品
-
(-)-Pinoresinol
(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
NSC622608
NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.
