BAY 2416964 ( —— )

产品货号. M22445 CAS No. 2242464-44-2

COA

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产品名称

BAY 2416964
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
产品描述

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
同义词

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通路

Others
靶点

Other Targets
受体

Aryl hydrocarbon receptor
研究领域

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适应症

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1. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1.

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